In this experiment, various LabView VIs were utilized to calibrate pH meter, enable PID control, and manually command pumps to alter the pH in a buffer solution. Using different proportions and combinations of PID control, properties of different combinations of P, PI, PD, and PID control, and near optimal results for each combination, were found. The parameters of interest were effects of the various combinations of PID control on pH, and how these parameters could be optimized to work in a bioreactor. The purpose of the experiment is to find the most suitable response control of changing the PH of the solution, from the original point to a set point of 6.5. Properties of P, PI, and PD control were measured as well as PID properties to compare efficiency of those controllers to PID. Proportional control alone demonstrated control of mainly offset and response speed, PI control cut out offset, but showed oscillations and overshoot, and PD control indicated control over oscillations and overshoot, but still gave way to offset. An optimal combination of proportional band (P), response time (I), and derivative time (D) eliminated offset, overshoot, and oscillations, and response time was minimized to a point where these errors in control do not arise.