Prevention of cancer metastasis through radiation treatment is widely acknowledged as an efficient method of patient care. However, researchers from Canada have discovered that specific tumors lack estrogen receptors, progesterone receptors, and human epidermal growth factor receptor 2. This makes these tumors resistant to the medication involved in radiation therapy and introduces the search for new methods of treatment. Further research has shown the effectiveness of a gene known as the twist-1 gene, which regulates the function of two proteins that play a key role in cancer metastasis: N-Cadherin and E-Cadherin. N-Cadherin is responsible for pulling epithelial cells apart while E-Cadherin binds epithelial cells together. After searching for the best methods to inactivate the twist-1 gene, we have come with two possible conclusions: using viruses to splice the DNA region containing the twist-1 gene and using the SRC-1 protein as a transcription factor. It is known that the use of the SRC-1 protein is more efficient; however, it is also understood that either of these methods can potentially treat cancer cells in any region containing epithelial cells.